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In epithelial cancers, aberrant COL17A1 promoter methylation predicts its misexpression and increased invasion

BACKGROUND: Metastasis is a leading cause of death among cancer patients. In the tumor microenvironment, altered levels of extracellular matrix proteins, such as collagens, can facilitate the first steps of cancer cell metastasis, including invasion into surrounding tissue and intravasation into the...

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Podrobná bibliografie
Vydáno v:Clin Epigenetics
Hlavní autoři: Thangavelu, Pulari U., Krenács, Tibor, Dray, Eloise, Duijf, Pascal H. G.
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5116176/
https://ncbi.nlm.nih.gov/pubmed/27891193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-016-0290-6
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