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In epithelial cancers, aberrant COL17A1 promoter methylation predicts its misexpression and increased invasion

BACKGROUND: Metastasis is a leading cause of death among cancer patients. In the tumor microenvironment, altered levels of extracellular matrix proteins, such as collagens, can facilitate the first steps of cancer cell metastasis, including invasion into surrounding tissue and intravasation into the...

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Bibliografski detalji
Izdano u:Clin Epigenetics
Glavni autori: Thangavelu, Pulari U., Krenács, Tibor, Dray, Eloise, Duijf, Pascal H. G.
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5116176/
https://ncbi.nlm.nih.gov/pubmed/27891193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-016-0290-6
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