Contradictory mRNA and protein misexpression of EEF1A1 in ductal breast carcinoma due to cell cycle regulation and cellular stress

Encoded by EEF1A1, the eukaryotic translation elongation factor eEF1α1 strongly promotes the heat shock response, which protects cancer cells from proteotoxic stress, following for instance oxidative stress, hypoxia or aneuploidy. Unexpectedly, therefore, we find that EEF1A1 mRNA levels are reduced...

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Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Lin, Cheng-Yu, Beattie, Alexandra, Baradaran, Behzad, Dray, Eloise, Duijf, Pascal H. G.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2018
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6141510/
https://ncbi.nlm.nih.gov/pubmed/30224719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-32272-x
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