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Streamlined ex vivo and in vivo genome editing in mouse embryos using recombinant adeno-associated viruses
Recent advances using CRISPR-Cas9 approaches have dramatically enhanced the ease for genetic manipulation in rodents. Notwithstanding, the methods to deliver nucleic acids into pre-implantation embryos have hardly changed since the original description of mouse transgenesis more than 30 years ago. H...
Shranjeno v:
| izdano v: | Nat Commun |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group UK
2018
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5788975/ https://ncbi.nlm.nih.gov/pubmed/29379011 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-02706-7 |
| Oznake: |
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