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Slow Infusion of Recombinant Adeno-Associated Viruses into the Mouse Cerebrospinal Fluid Space

Recombinant adeno-associated viruses (rAAVs) are the leading in vivo gene delivery platform, and have been extensively studied in gene therapy targeting various tissues, including the central nervous system (CNS). A single-bolus rAAV injection to the cerebrospinal fluid (CSF) space has been widely u...

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Detalles Bibliográficos
Publicado en:Hum Gene Ther Methods
Main Authors: Wang, Dan, Li, Jia, Tran, Karen, Burt, Daniel R., Zhong, Li, Gao, Guangping
Formato: Artigo
Idioma:Inglês
Publicado: Mary Ann Liebert, Inc. 2018
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5910051/
https://ncbi.nlm.nih.gov/pubmed/29596011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hgtb.2017.250
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