載入...
Treatment-associated TP53 DNA-binding domain missense mutations in the pathogenesis of secondary gliosarcoma
BACKGROUND: Gliosarcoma is a rare variant of glioblastoma (GBM) that exhibits frequent mutations in TP53 and can develop in a secondary fashion after chemoradiation of a primary GBM. Whether temozolomide (TMZ)-induced mutagenesis of the TP53 DNA-binding domain (DBD) can drive the pathogenesis of gli...
Na minha lista:
發表在: | Oncotarget |
---|---|
Main Authors: | , , , , , , , |
格式: | Artigo |
語言: | Inglês |
出版: |
Impact Journals LLC
2017
|
主題: | |
在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5788663/ https://ncbi.nlm.nih.gov/pubmed/29416795 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.23517 |
標簽: |
添加標簽
沒有標簽, 成為第一個標記此記錄!
|