Peroxynitrite preferentially oxidizes the dithiol redox motifs of protein-disulfide isomerase

Protein-disulfide isomerase (PDI) is a ubiquitous dithiol–disulfide oxidoreductase that performs an array of cellular functions, such as cellular signaling and responses to cell-damaging events. PDI can become dysfunctional by post-translational modifications, including those promoted by biological...

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Bibliografische gegevens
Gepubliceerd in:J Biol Chem
Hoofdauteurs: Peixoto, Álbert Souza, Geyer, R. Ryan, Iqbal, Asif, Truzzi, Daniela R., Soares Moretti, Ana I., Laurindo, Francisco R. M., Augusto, Ohara
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Biochemistry and Molecular Biology 2018
Onderwerpen:
Enzymology
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5787819/
https://ncbi.nlm.nih.gov/pubmed/29191937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.807016
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