The dual PI3K/mTOR inhibitor dactolisib elicits anti-tumor activity in vitro and in vivo

Glioblastomas (GBMs) are among the most malignant of all human tumors and have poor prognosis. The current standard of care (SOC) includes maximal surgical tumor resection followed by adjuvant temozolomide (TMZ) and concomitant radiotherapy (RT). However, even with this treatment, the 5-year surviva...

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Опубликовано в: :Oncotarget
Главные авторы: Shi, Fei, Zhang, Jinying, Liu, Hongyu, Wu, Liangliang, Jiang, Hongyu, Wu, Qiyan, Liu, Tianyi, Lou, Meiqing, Wu, Hao
Формат: Artigo
Язык:Inglês
Опубликовано: Impact Journals LLC 2017
Предметы:
Research Paper
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5787502/
https://ncbi.nlm.nih.gov/pubmed/29416647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.23091
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