The dual PI3K/mTOR inhibitor dactolisib elicits anti-tumor activity in vitro and in vivo

Glioblastomas (GBMs) are among the most malignant of all human tumors and have poor prognosis. The current standard of care (SOC) includes maximal surgical tumor resection followed by adjuvant temozolomide (TMZ) and concomitant radiotherapy (RT). However, even with this treatment, the 5-year surviva...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Shi, Fei, Zhang, Jinying, Liu, Hongyu, Wu, Liangliang, Jiang, Hongyu, Wu, Qiyan, Liu, Tianyi, Lou, Meiqing, Wu, Hao
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5787502/
https://ncbi.nlm.nih.gov/pubmed/29416647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.23091
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