PINK1 suppresses alpha-synuclein-induced neuronal injury: a novel mechanism in protein phosphatase 2A activation

Alpha-synuclein (α-Syn) and phosphatase and tensin homolog deleted on chromosome ten (PTEN)-induced putative kinase (PINK) 1 are proteins found in Lewy bodies, which are a pathological hallmark of Parkinson’s disease (PD). PINK1 overexpression suppresses α-Syn-induced phenotypes and increases lifesp...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Oncotarget
Hlavní autoři: Yang, Weiwei, Wang, Xue, Liu, Jia, Duan, Chunli, Gao, Ge, Lu, Lingling, Yu, Shun, Yang, Hui
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2017
Témata:
Research Paper: Gerotarget (Focus on Aging)
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5787472/
https://ncbi.nlm.nih.gov/pubmed/29416594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.21554
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky