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A cDNA Immunization Strategy to Generate Nanobodies against Membrane Proteins in Native Conformation
Nanobodies (Nbs) are soluble, versatile, single-domain binding modules derived from the VHH variable domain of heavy-chain antibodies naturally occurring in camelids. Nbs hold huge promise as novel therapeutic biologics. Membrane proteins are among the most interesting targets for therapeutic Nbs be...
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| Publicado no: | Front Immunol |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5787055/ https://ncbi.nlm.nih.gov/pubmed/29410663 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.01989 |
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