Highly selective inhibition of Bruton’s tyrosine kinase attenuates skin and brain disease in murine lupus

BACKGROUND: Systemic lupus erythematosus (SLE) is a systemic autoimmune disease that affects different end organs, including skin and brain. We and others have previously shown the importance of macrophages in the pathogenesis of cutaneous and neuropsychiatric lupus. Additionally, autoantibodies pro...

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Detalhes bibliográficos
Publicado no:Arthritis Res Ther
Main Authors: Chalmers, Samantha A., Wen, Jing, Doerner, Jessica, Stock, Ariel, Cuda, Carla M., Makinde, Hadijat M., Perlman, Harris, Bosanac, Todd, Webb, Deborah, Nabozny, Gerald, Fine, Jay S., Klein, Elliott, Ramanujam, Meera, Putterman, Chaim
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5785891/
https://ncbi.nlm.nih.gov/pubmed/29370834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-017-1500-0
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