BTK inhibition ameliorates kidney disease in spontaneous lupus nephritis

Lupus nephritis is a common disease manifestation of SLE, in which immune complex deposition and macrophage activation are important contributors to disease pathogenesis. Bruton’s tyrosine kinase (BTK) plays an important role in both B cell and FcgammaR mediated myeloid cell activation. In the curre...

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Publicado no:Clin Immunol
Main Authors: Chalmers, Samantha A., Glynn, Elizabeth, Garcia, Sayra J., Panzenbeck, Mark, Pelletier, Josephine, Dimock, Janice, Seccareccia, Elise, Bosanac, Todd, Khalil, Sara, Harcken, Christian, Webb, Deborah, Nabozny, Gerald, Fine, Jay S., Souza, Donald, Klein, Elliott, Herlitz, Leal, Ramanujam, Meera, Putterman, Chaim
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6384222/
https://ncbi.nlm.nih.gov/pubmed/30339790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clim.2018.10.008
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