Deep learning for discovering pathological continuum of crypts and evaluating therapeutic effects: An implication for in vivo preclinical study

par Shan, Dechao, Zheng, Jie, Klimowicz, Alexander, Panzenbeck, Mark, Liu, Zheng, Feng, Di
Publié dans PLoS One (2021)

The oxidase activity of vascular adhesion protein-1 (VAP-1) is essential for function

par Noonan, Thomas, Lukas, Susan, Peet, Gregory W, Pelletier, Josephine, Panzenbeck, Mark, Hanidu, Adedayo, Mazurek, Suzanne, Wasti, Ruby, Rybina, Irina, Roma, Teresa, Kronkaitis, Anthony, Shoultz, Alycia, Souza, Donald, Jiang, Huiping, Nabozny, Gerald, Modis, Louise Kelly
Publié 2013

BTK inhibition ameliorates kidney disease in spontaneous lupus nephritis

par Chalmers, Samantha A., Glynn, Elizabeth, Garcia, Sayra J., Panzenbeck, Mark, Pelletier, Josephine, Dimock, Janice, Seccareccia, Elise, Bosanac, Todd, Khalil, Sara, Harcken, Christian, Webb, Deborah, Nabozny, Gerald, Fine, Jay S., Souza, Donald, Klein, Elliott, Herlitz, Leal, Ramanujam, Meera, Putterman, Chaim
Publié dans Clin Immunol (2018)

Fecal MicroRNAs Show Promise as Noninvasive Crohn’s Disease Biomarkers

par Wohnhaas, Christian T, Schmid, Ramona, Rolser, Marcel, Kaaru, Eric, Langgartner, Dominik, Rieber, Kathrin, Strobel, Benjamin, Eisele, Claudia, Wiech, Franziska, Jakob, Ines, Gantner, Florian, Herichova, Ivona, Vinisko, Richard, Böcher, Wulf O, Visvanathan, Sudha, Shen, Fei, Panzenbeck, Mark, Raymond, Ernest, Reber, Stefan O, Delić, Denis, Baum, Patrick
Publié dans Crohns Colitis 360 (2020)

CCR1 Plays a Critical Role in Modulating Pain through Hematopoietic and Non-Hematopoietic Cells

par Lewis, Nuruddeen D., Muthukumarana, Akalushi, Fogal, Steven E., Corradini, Laura, Stefanopoulos, Dimitria E., Adusumalli, Prathima, Pelletier, Josephine, Panzenbeck, Mark, Berg, Karen, Canfield, Melissa, Cook, Brian N., Razavi, Hossein, Kuzmich, Daniel, Anderson, Shawn, Allard, Devan, Harrison, Paul, Grimaldi, Christine, Souza, Donald, Harcken, Christian, Fryer, Ryan M., Modis, Louise K., Brown, Maryanne L.
Publié 2014

An RORγt Oral Inhibitor Modulates IL-17 Responses in Peripheral Blood and Intestinal Mucosa of Crohn's Disease Patients

par Bassolas-Molina, Helena, Raymond, Ernest, Labadia, Mark, Wahle, Joseph, Ferrer-Picón, Elena, Panzenbeck, Mark, Zheng, Jie, Harcken, Christian, Hughes, Robert, Turner, Michael, Smith, Dustin, Calderón-Gómez, Elisabeth, Esteller, Míriam, Carrasco, Anna, Esteve, Maria, Dotti, Isabella, Corraliza, Ana Maria, Masamunt, Maria Carme, Arajol, Clàudia, Guardiola, Jordi, Ricart, Elena, Nabozny, Gerald, Salas, Azucena
Publié dans Front Immunol (2018)

Discovery of a Series of Pyrazinone RORγ Antagonists and Identification of the Clinical Candidate BI 730357

par Harcken, Christian, Csengery, Johanna, Turner, Michael, Wu, Lifen, Liang, Shuang, Sibley, Robert, Brunette, Steven, Labadia, Mark, Hoyt, Kathleen, Wayne, Anita, Wieckowski, Thomas, Davis, Gregg, Panzenbeck, Mark, Souza, Donald, Kugler, Stanley, Terenzio, Donna, Collin, Delphine, Smith, Dustin, Fryer, Ryan M., Tseng, Yin-Chao, Hehn, Jörg P., Fletcher, Kim, Hughes, Robert O.
Publié dans ACS Med Chem Lett (2021)

Indole Inhibitors of MMP-13 for Arthritic Disorders

par Taylor, Steven J., Abeywardane, Asitha, Liang, Shuang, Xiong, Zhaoming, Proudfoot, John R., Farmer, Bennett Sandy, Gao, Donghong A., Heim-Riether, Alexander, Smith-Keenan, Lana Louise, Muegge, Ingo, Yu, Yang, Zhang, Qiang, Souza, Donald, Panzenbeck, Mark, Goldberg, Daniel, Hill-Drzewi, Melissa, Margarit, Mariana, Collins, Brandon, Li, John Xiang, Zuvela-Jelaska, Ljiljana, Li, Jun, Farrow, Neil A.
Publié dans ACS Omega (2021)