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REDOR NMR Reveals Multiple Conformers for a Protein Kinase C Ligand in a Membrane Environment
[Image: see text] Bryostatin 1 (henceforth bryostatin) is in clinical trials for the treatment of Alzheimer’s disease and for HIV/AIDS eradication. It is also a preclinical lead for cancer immunotherapy and other therapeutic indications. Yet nothing is known about the conformation of bryostatin boun...
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| Pubblicato in: | ACS Cent Sci |
|---|---|
| Autori principali: | , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American
Chemical Society
2018
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| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5785774/ https://ncbi.nlm.nih.gov/pubmed/29392180 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acscentsci.7b00475 |
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