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Influenza-specific lung-resident memory T cells are proliferative and polyfunctional and maintain diverse TCR profiles

The human lung harbors a large population of resident memory T cells (Trm cells). These cells are perfectly positioned to mediate rapid protection against respiratory pathogens such as influenza virus, a highly contagious respiratory pathogen that continues to be a major public health burden. Animal...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Pizzolla, Angela, Nguyen, Thi H.O., Sant, Sneha, Jaffar, Jade, Loudovaris, Tom, Mannering, Stuart I., Thomas, Paul G., Westall, Glen P., Kedzierska, Katherine, Wakim, Linda M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5785253/
https://ncbi.nlm.nih.gov/pubmed/29309047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI96957
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