Influenza, but not SARS‐CoV‐2, infection induces a rapid interferon response that wanes with age and diminished tissue‐resident memory CD8(+) T cells

Older individuals exhibit a diminished ability to respond to and clear respiratory pathogens and, as such, experience a higher rate of lung infections with a higher mortality rate. It is unclear why respiratory pathogens impact older people disproportionately. Using human lung tissue from donors age...

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Vydáno v:Clin Transl Immunology
Hlavní autoři: Nguyen, Thi HO, McAuley, Julie L, Kim, Youry, Zheng, Ming ZM, Gherardin, Nicholas A, Godfrey, Dale I, Purcell, Damian FJ, Sullivan, Lucy C, Westall, Glen P, Reading, Patrick C, Kedzierska, Katherine, Wakim, Linda M
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2021
Témata:
Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7837404/
https://ncbi.nlm.nih.gov/pubmed/33532071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cti2.1242
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