Influenza, but not SARS‐CoV‐2, infection induces a rapid interferon response that wanes with age and diminished tissue‐resident memory CD8(+) T cells

Older individuals exhibit a diminished ability to respond to and clear respiratory pathogens and, as such, experience a higher rate of lung infections with a higher mortality rate. It is unclear why respiratory pathogens impact older people disproportionately. Using human lung tissue from donors age...

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Detalhes bibliográficos
Publicado no:Clin Transl Immunology
Main Authors: Nguyen, Thi HO, McAuley, Julie L, Kim, Youry, Zheng, Ming ZM, Gherardin, Nicholas A, Godfrey, Dale I, Purcell, Damian FJ, Sullivan, Lucy C, Westall, Glen P, Reading, Patrick C, Kedzierska, Katherine, Wakim, Linda M
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7837404/
https://ncbi.nlm.nih.gov/pubmed/33532071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cti2.1242
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