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The host protecting the tumor from the host — targeting PD‑L1 expressed by host cells
Tumors frequently escape from immune surveillance by hijacking the natural control mechanisms that regulate normal immune responses. The programmed death-1 receptor (PD‑1) on T cells normally helps limit excessive immune activation, but it can also suppress beneficial antitumor immunity. In the clin...
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| Publicado no: | J Clin Invest |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5785247/ https://ncbi.nlm.nih.gov/pubmed/29337304 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI99047 |
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