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A compensatory mutagenesis study of a conserved hairpin in the M gene segment of influenza A virus shows its role in virus replication

RNA structures are increasingly recognized to be of importance during influenza A virus replication. Here, we investigated a predicted conserved hairpin in the M gene segment (nt 967-994) within the region of the vRNA 5′ packaging signal. The existence of this RNA structure and its possible role in...

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Publicado en:RNA Biol
Main Authors: Spronken, M. I., van de Sandt, C. E., de Jongh, E. P., Vuong, O., van der Vliet, S., Bestebroer, T. M., Olsthoorn, R. C. L., Rimmelzwaan, G. F., Fouchier, R.A. M., Gultyaev, A. P.
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5785231/
https://ncbi.nlm.nih.gov/pubmed/28662365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2017.1338243
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