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Conserved structural RNA domains in regions coding for cleavage site motifs in hemagglutinin genes of influenza viruses

The acquisition of a multibasic cleavage site (MBCS) in the hemagglutinin (HA) glycoprotein is the main determinant of the conversion of low pathogenic avian influenza viruses into highly pathogenic strains, facilitating HA cleavage and virus replication in a broader range of host cells. In nature,...

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Detalhes bibliográficos
Publicado no:Virus Evol
Main Authors: Gultyaev, Alexander P, Richard, Mathilde, Spronken, Monique I, Olsthoorn, René C L, Fouchier, Ron A M
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6704317/
https://ncbi.nlm.nih.gov/pubmed/31456885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ve/vez034
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