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Subtype-specific structural constraints in the evolution of influenza A virus hemagglutinin genes

The influenza A virus genome consists of eight RNA segments. RNA structures within these segments and complementary (cRNA) and protein-coding mRNAs may play a role in virus replication. Here, conserved putative secondary structures that impose significant evolutionary constraints on the gene segment...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Gultyaev, Alexander P., Spronken, Monique I., Richard, Mathilde, Schrauwen, Eefje J. A., Olsthoorn, René C. L., Fouchier, Ron A. M.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5155281/
https://ncbi.nlm.nih.gov/pubmed/27966593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep38892
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