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Amino Acid Substitutions That Affect Receptor Binding and Stability of the Hemagglutinin of Influenza A/H7N9 Virus

Receptor-binding preference and stability of hemagglutinin have been implicated as crucial determinants of airborne transmission of influenza viruses. Here, amino acid substitutions previously identified to affect these traits were tested in the context of an A/H7N9 virus. Some combinations of subst...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Schrauwen, Eefje J. A., Richard, Mathilde, Burke, David F., Rimmelzwaan, Guus F., Herfst, Sander, Fouchier, Ron A. M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4794686/
https://ncbi.nlm.nih.gov/pubmed/26792744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03052-15
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