Accumulation of Amino Acid Substitutions Promotes Irreversible Structural Changes in the Hemagglutinin of Human Influenza AH3 Virus during Evolution

In order to clarify the effect of an accumulation of amino acid substitutions on the hemadsorption character of the influenza AH3 virus hemagglutinin (HA) protein, we introduced single-point amino acid changes into the HA1 domain of the HA proteins of influenza viruses isolated in 1968 (A/Aichi/2/68...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Nakajima, Katsuhisa, Nobusawa, Eri, Nagy, Alexander, Nakajima, Setsuko
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2005
Témata:
Genetic Diversity and Evolution
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1091720/
https://ncbi.nlm.nih.gov/pubmed/15858030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.10.6472-6477.2005
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky