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A compensatory mutagenesis study of a conserved hairpin in the M gene segment of influenza A virus shows its role in virus replication

RNA structures are increasingly recognized to be of importance during influenza A virus replication. Here, we investigated a predicted conserved hairpin in the M gene segment (nt 967-994) within the region of the vRNA 5′ packaging signal. The existence of this RNA structure and its possible role in...

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Bibliographische Detailangaben
Veröffentlicht in:RNA Biol
Hauptverfasser: Spronken, M. I., van de Sandt, C. E., de Jongh, E. P., Vuong, O., van der Vliet, S., Bestebroer, T. M., Olsthoorn, R. C. L., Rimmelzwaan, G. F., Fouchier, R.A. M., Gultyaev, A. P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5785231/
https://ncbi.nlm.nih.gov/pubmed/28662365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2017.1338243
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