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The reliability of molecular dynamics simulations of the multidrug transporter P-glycoprotein in a membrane environment

Despite decades of research, the mechanism of action of the ABC multidrug transporter P-glycoprotein (P-gp) remains elusive. Due to experimental limitations, many researchers have turned to molecular dynamics simulation studies in order to investigate different aspects of P-gp function. However, suc...

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Bibliografiska uppgifter
I publikationen:PLoS One
Huvudupphovsmän: Condic-Jurkic, Karmen, Subramanian, Nandhitha, Mark, Alan E., O’Mara, Megan L.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2018
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5785007/
https://ncbi.nlm.nih.gov/pubmed/29370310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0191882
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