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Structural Characterization of Two Metastable ATP-Bound States of P-Glycoprotein

ATP Binding Cassette (ABC) transporters couple the binding and hydrolysis of ATP to the transport of substrate molecules across the membrane. The mechanism by which ATP binding and/or hydrolysis drives the conformational changes associated with substrate transport has not yet been characterized full...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: O’Mara, Megan L., Mark, Alan E.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2014
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3954865/
https://ncbi.nlm.nih.gov/pubmed/24632881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0091916
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