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Structural Characterization of Two Metastable ATP-Bound States of P-Glycoprotein
ATP Binding Cassette (ABC) transporters couple the binding and hydrolysis of ATP to the transport of substrate molecules across the membrane. The mechanism by which ATP binding and/or hydrolysis drives the conformational changes associated with substrate transport has not yet been characterized full...
Sparad:
| Huvudupphovsmän: | , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
Public Library of Science
2014
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3954865/ https://ncbi.nlm.nih.gov/pubmed/24632881 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0091916 |
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