Antifibrotic effect of xanthohumol in combination with praziquantel is associated with altered redox status and reduced iron accumulation during liver fluke-associated cholangiocarcinogenesis

Cholangiocarcinoma (CCA) caused by infection of the liver fluke Opisthorchis viverrini, (Ov) is the major public health problem in northeast Thailand. Following Ov infection the subsequent molecular changes can be associated by reactive oxygen species (ROS) induced chronic inflammation, advanced per...

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Detalhes bibliográficos
Publicado no:PeerJ
Main Authors: Jamnongkan, Wassana, Thanee, Malinee, Yongvanit, Puangrat, Loilome, Watcharin, Thanan, Raynoo, Kimawaha, Phongsaran, Boonmars, Tidarat, Silakit, Runglawan, Namwat, Nisana, Techasen, Anchalee
Formato: Artigo
Idioma:Inglês
Publicado em: PeerJ Inc. 2018
Assuntos:
Molecular Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5784579/
https://ncbi.nlm.nih.gov/pubmed/29375936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.4281
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