Antifibrotic effect of xanthohumol in combination with praziquantel is associated with altered redox status and reduced iron accumulation during liver fluke-associated cholangiocarcinogenesis

Cholangiocarcinoma (CCA) caused by infection of the liver fluke Opisthorchis viverrini, (Ov) is the major public health problem in northeast Thailand. Following Ov infection the subsequent molecular changes can be associated by reactive oxygen species (ROS) induced chronic inflammation, advanced per...

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Dettagli Bibliografici
Pubblicato in:PeerJ
Autori principali: Jamnongkan, Wassana, Thanee, Malinee, Yongvanit, Puangrat, Loilome, Watcharin, Thanan, Raynoo, Kimawaha, Phongsaran, Boonmars, Tidarat, Silakit, Runglawan, Namwat, Nisana, Techasen, Anchalee
Natura: Artigo
Lingua:Inglês
Pubblicazione: PeerJ Inc. 2018
Soggetti:
Molecular Biology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5784579/
https://ncbi.nlm.nih.gov/pubmed/29375936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.4281
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