Antifibrotic effect of xanthohumol in combination with praziquantel is associated with altered redox status and reduced iron accumulation during liver fluke-associated cholangiocarcinogenesis

Cholangiocarcinoma (CCA) caused by infection of the liver fluke Opisthorchis viverrini, (Ov) is the major public health problem in northeast Thailand. Following Ov infection the subsequent molecular changes can be associated by reactive oxygen species (ROS) induced chronic inflammation, advanced per...

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Bibliographische Detailangaben
Veröffentlicht in:PeerJ
Hauptverfasser: Jamnongkan, Wassana, Thanee, Malinee, Yongvanit, Puangrat, Loilome, Watcharin, Thanan, Raynoo, Kimawaha, Phongsaran, Boonmars, Tidarat, Silakit, Runglawan, Namwat, Nisana, Techasen, Anchalee
Format: Artigo
Sprache:Inglês
Veröffentlicht: PeerJ Inc. 2018
Schlagworte:
Molecular Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5784579/
https://ncbi.nlm.nih.gov/pubmed/29375936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.4281
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