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IL-36/LXR axis modulates cholesterol metabolism and immune defense to Mycobacterium tuberculosis
Mycobacterium tuberculosis (Mtb) is a life-threatening pathogen in humans. Bacterial infection of macrophages usually triggers strong innate immune mechanisms, including IL-1 cytokine secretion. The newer member of the IL-1 family, IL-36, was recently shown to be involved in cellular defense against...
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| Pubblicato in: | Sci Rep |
|---|---|
| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group UK
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5784124/ https://ncbi.nlm.nih.gov/pubmed/29367626 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-19476-x |
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