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OS1.4 Current treatment regimens induce the mTORC1 inhibitor REDD1 in human glioblastoma cells: implications for treatment efficacy

Glioblastoma is an incurable brain cancer with median survival of less than 1 year in unselected cohorts. Current treatment options include surgical resection and radiotherapy, alkylating chemotherapy with temozolomide or nitrosoureas. Hypoxia and nutrient depletion in the tumor microenvironment are...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Neuro Oncol
Prif Awduron: Foltyn, M., Thiepold, A., Harter, P. N., Baumgarten, P., Mittelbronn, M., Urban, H., Steinbach, J. P., Ronellenfitsch, M. W.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5782506/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/now188.006
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