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P01.03 mTORC1 activation sensitizes human malignant glioma cells to hypoxia-induced cell death by increasing O2-consumption
Glioblastoma (GB) is an incurable brain cancer with median survival of less than one year in unselected cohorts. Current treatment of recurrent tumors frequently involves the VEGF-A-targeting antibody bevacizumab that causes local therapeutic hypoxia. After initial chemotherapy activating mutations...
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| 出版年: | Neuro Oncol |
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| 主要な著者: | , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5782559/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/now188.060 |
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