Immunohistochemical Assessment of Phosphorylated mTORC1-Pathway Proteins in Human Brain Tumors

BACKGROUND: Current pathological diagnostics include the analysis of (epi-)genetic alterations as well as oncogenic pathways. Deregulated mammalian target of rapamycin complex 1 (mTORC1) signaling has been implicated in a variety of cancers including malignant gliomas and is considered a promising t...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Harter, Patrick N., Jennewein, Lukas, Baumgarten, Peter, Ilina, Elena, Burger, Michael C., Thiepold, Anna-Luisa, Tichy, Julia, Zörnig, Martin, Senft, Christian, Steinbach, Joachim P., Mittelbronn, Michel, Ronellenfitsch, Michael W.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4437987/
https://ncbi.nlm.nih.gov/pubmed/25993328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0127123
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