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Lethal mutagenesis of an RNA plant virus via lethal defection

Lethal mutagenesis is an antiviral therapy that relies on increasing the viral mutation rate with mutagenic nucleoside or base analogues. Currently, the molecular mechanisms that lead to virus extinction through enhanced mutagenesis are not fully understood. Increasing experimental evidence supports...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Díaz-Martínez, Luis, Brichette-Mieg, Isabel, Pineño-Ramos, Axier, Domínguez-Huerta, Guillermo, Grande-Pérez, Ana
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5780445/
https://ncbi.nlm.nih.gov/pubmed/29362502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-19829-6
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