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Cdc73 suppresses genome instability by mediating telomere homeostasis
Defects in the genes encoding the Paf1 complex can cause increased genome instability. Loss of Paf1, Cdc73, and Ctr9, but not Rtf1 or Leo1, caused increased accumulation of gross chromosomal rearrangements (GCRs). Combining the cdc73Δ mutation with individual deletions of 43 other genes, including T...
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| 出版年: | PLoS Genet |
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| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Public Library of Science
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5779705/ https://ncbi.nlm.nih.gov/pubmed/29320491 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1007170 |
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