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The Swr1 chromatin-remodeling complex prevents genome instability induced by replication fork progression defects
Genome instability is associated with tumorigenesis. Here, we identify a role for the histone Htz1, which is deposited by the Swr1 chromatin-remodeling complex (SWR-C), in preventing genome instability in the absence of the replication fork/replication checkpoint proteins Mrc1, Csm3, or Tof1. When c...
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| Publicado no: | Nat Commun |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6134005/ https://ncbi.nlm.nih.gov/pubmed/30206225 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-06131-2 |
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