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Post-Replication Repair Suppresses Duplication-Mediated Genome Instability

RAD6 is known to suppress duplication-mediated gross chromosomal rearrangements (GCRs) but not single-copy sequence mediated GCRs. Here, we found that the RAD6- and RAD18-dependent post-replication repair (PRR) and the RAD5-, MMS2-, UBC13-dependent error-free PRR branch acted in concert with the rep...

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Detalhes bibliográficos
Main Authors: Putnam, Christopher D., Hayes, Tikvah K., Kolodner, Richard D.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2865514/
https://ncbi.nlm.nih.gov/pubmed/20463880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000933
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