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Bioinformatic identification of genes suppressing genome instability

Unbiased forward genetic screens for mutations causing increased gross chromosomal rearrangement (GCR) rates in Saccharomyces cerevisiae are hampered by the difficulty in reliably using qualitative GCR assays to detect mutants with small but significantly increased GCR rates. We therefore developed...

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Detalhes bibliográficos
Main Authors: Putnam, Christopher D., Allen-Soltero, Stephanie R., Martinez, Sandra L., Chan, Jason E., Hayes, Tikvah K., Kolodner, Richard D.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3511103/
https://ncbi.nlm.nih.gov/pubmed/23129647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1216733109
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