Essential Saccharomyces cerevisiae genome instability suppressing genes identify potential human tumor suppressors

Gross Chromosomal Rearrangements (GCRs) play an important role in human diseases, including cancer. Although most of the nonessential Genome Instability Suppressing (GIS) genes in Saccharomyces cerevisiae are known, the essential genes in which mutations can cause increased GCR rates are not well un...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Srivatsan, Anjana, Li, Binzhong, Sanchez, Dafne N., Somach, Steven B., da Silva, Vandeclecio L., de Souza, Sandro J., Putnam, Christopher D., Kolodner, Richard D.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2019
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6717276/
https://ncbi.nlm.nih.gov/pubmed/31409704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1906921116
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