Essential Saccharomyces cerevisiae genome instability suppressing genes identify potential human tumor suppressors

Gross Chromosomal Rearrangements (GCRs) play an important role in human diseases, including cancer. Although most of the nonessential Genome Instability Suppressing (GIS) genes in Saccharomyces cerevisiae are known, the essential genes in which mutations can cause increased GCR rates are not well un...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Srivatsan, Anjana, Li, Binzhong, Sanchez, Dafne N., Somach, Steven B., da Silva, Vandeclecio L., de Souza, Sandro J., Putnam, Christopher D., Kolodner, Richard D.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2019
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6717276/
https://ncbi.nlm.nih.gov/pubmed/31409704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1906921116
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