Essential Saccharomyces cerevisiae genome instability suppressing genes identify potential human tumor suppressors

Gross Chromosomal Rearrangements (GCRs) play an important role in human diseases, including cancer. Although most of the nonessential Genome Instability Suppressing (GIS) genes in Saccharomyces cerevisiae are known, the essential genes in which mutations can cause increased GCR rates are not well un...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Srivatsan, Anjana, Li, Binzhong, Sanchez, Dafne N., Somach, Steven B., da Silva, Vandeclecio L., de Souza, Sandro J., Putnam, Christopher D., Kolodner, Richard D.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2019
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6717276/
https://ncbi.nlm.nih.gov/pubmed/31409704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1906921116
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