A genetic network that suppresses genome rearrangements in Saccharomyces cerevisiae and contains defects in cancers

Gross chromosomal rearrangements (GCRs) play an important role in human diseases, including cancer. The identity of all Genome Instability Suppressing (GIS) genes is not currently known. Here multiple Saccharomyces cerevisiae GCR assays and query mutations were crossed into arrays of mutants to iden...

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Udgivet i:Nat Commun
Main Authors: Putnam, Christopher D., Srivatsan, Anjana, Nene, Rahul V., Martinez, Sandra L., Clotfelter, Sarah P., Bell, Sara N., Somach, Steven B., E.S. de Souza, Jorge, Fonseca, André F., de Souza, Sandro J., Kolodner, Richard D.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4833866/
https://ncbi.nlm.nih.gov/pubmed/27071721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11256
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