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Modulating Cell-Surface Receptor Signaling and Ion Channel Functions by In Situ Glycan Editing
Glycans anchored on cell-surface receptors are active modulators of receptor signaling. A strategy is presented that enforces transient changes to cell-surface glycosylation patterns to tune receptor signaling. This approach, termed in situ glycan editing, exploits recombinant glycosyltransferases t...
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| Veröffentlicht in: | Angew Chem Int Ed Engl |
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| Hauptverfasser: | , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5779621/ https://ncbi.nlm.nih.gov/pubmed/29292859 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201706535 |
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