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Tracking surface glycans on live cancer cells with single molecule sensitivity()

Using a combination of metabolically labeled glycans, bioorthogonal Cu(I)-catalyzed azide-alkyne cycloaddition and controlled bleaching of fluorescent probes conjugated to azide or alkyne tagged glycans, we achieve a sufficiently low spatial density of dye labeled glycans enabling dynamic single-mol...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Angew Chem Int Ed Engl
Egile Nagusiak: Jiang, Hao, English, Brian P., Hazan, Rachel B., Wu, Peng, Ovryn, Ben
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2014
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4465920/
https://ncbi.nlm.nih.gov/pubmed/25515330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201407976
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