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Mapping translation 'hot-spots' in live cells by tracking single molecules of mRNA and ribosomes

Messenger RNA localization is important for cell motility by local protein translation. However, while single mRNAs can be imaged and their movements tracked in single cells, it has not yet been possible to determine whether these mRNAs are actively translating. Therefore, we imaged single β-actin m...

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Bibliografiske detaljer
Udgivet i:eLife
Main Authors: Katz, Zachary B, English, Brian P, Lionnet, Timothée, Yoon, Young J, Monnier, Nilah, Ovryn, Ben, Bathe, Mark, Singer, Robert H
Format: Artigo
Sprog:Inglês
Udgivet: eLife Sciences Publications, Ltd 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4764586/
https://ncbi.nlm.nih.gov/pubmed/26760529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.10415
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