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Mapping translation 'hot-spots' in live cells by tracking single molecules of mRNA and ribosomes

Messenger RNA localization is important for cell motility by local protein translation. However, while single mRNAs can be imaged and their movements tracked in single cells, it has not yet been possible to determine whether these mRNAs are actively translating. Therefore, we imaged single β-actin m...

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Dades bibliogràfiques
Publicat a:eLife
Autors principals: Katz, Zachary B, English, Brian P, Lionnet, Timothée, Yoon, Young J, Monnier, Nilah, Ovryn, Ben, Bathe, Mark, Singer, Robert H
Format: Artigo
Idioma:Inglês
Publicat: eLife Sciences Publications, Ltd 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4764586/
https://ncbi.nlm.nih.gov/pubmed/26760529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.10415
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