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Partial bisulfite conversion for unique template sequencing
We introduce a new protocol, mutational sequencing or muSeq, which uses sodium bisulfite to randomly deaminate unmethylated cytosines at a fixed and tunable rate. The muSeq protocol marks each initial template molecule with a unique mutation signature that is present in every copy of the template, a...
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| I publikationen: | Nucleic Acids Res |
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| Huvudupphovsmän: | , , , , , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
Oxford University Press
2018
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5778454/ https://ncbi.nlm.nih.gov/pubmed/29161423 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx1054 |
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