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Enantioselective Iridium Catalyzed Phthalide Formation via Internal Redox Allylation of Phthalaldehydes()

Enantioselective phthalide synthesis is achieved through internal redox allylation of o-phthalaldehydes. Oxidative esterification is balanced by reductive carbonyl addition to achieve an overall redox neutral process. Using this method, formal syntheses of ent-spirolaxine methyl ether and CJ-12,954...

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Publicat a:Angew Chem Int Ed Engl
Autors principals: Cabrera, James M., Tauber, Johannes, Krische, Michael J.
Format: Artigo
Idioma:Inglês
Publicat: 2018
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5777894/
https://ncbi.nlm.nih.gov/pubmed/29240280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201712015
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