Hypoxia-activated prodrug enhances therapeutic effect of sunitinib in melanoma

Angiogenesis is a critical step during tumor progression. Anti-angiogenic therapy has only provided modest benefits in delaying tumor progression despite its early promise in cancer treatment. It has been postulated that anti-angiogenic therapy may promote the emergence of a more aggressive cancer c...

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Bibliographische Detailangaben
Veröffentlicht in:Oncotarget
Hauptverfasser: Liu, Shujing, Tetzlaff, Michael T., Wang, Tao, Chen, Xiang, Yang, Ruifeng, Kumar, Suresh M., Vultur, Adina, Li, Pengxiang, Martin, James S., Herlyn, Meenhard, Amaravadi, Ravi, Li, Bin, Xu, Xiaowei
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2017
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5777760/
https://ncbi.nlm.nih.gov/pubmed/29383148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.22944
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