CKS protein overexpression renders tumors susceptible to a chemotherapeutic strategy that protects normal tissues

The cyclin-dependent kinase-interacting proteins Cyclin-dependent Kinase Subunit 1 and 2 (CKS1 and 2) are frequently overexpressed in cancer and linked to increased aggressiveness and poor prognoses. We previously showed that CKS protein overexpression overrides the replication stress checkpoint act...

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Bibliographic Details
Published in:Oncotarget
Main Authors: Tat, John, Loriot, Céline, Henze, Martha, Spruck, Charles, Felding, Brunhilde H., Reed, Steven I.
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2017
Subjects:
Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5777741/
https://ncbi.nlm.nih.gov/pubmed/29383129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.22931
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