Proteasome and heat shock protein 70 (HSP70) inhibitors as therapeutic alternative in multiple myeloma

HSP70 connects multiple signaling pathways that work synergistically to protect tumor cells from death by proteotoxic stress and represents a possible target to establish a new approach for multiple myeloma treatment. Therefore, bioluminescent cell lines RPMI8226-LUC-PURO and U266-LUC-PURO were trea...

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Dettagli Bibliografici
Pubblicato in:Oncotarget
Autori principali: Eugênio, Angela Isabel Pereira, Fook-Alves, Veruska Lia, de Oliveira, Mariana Bleker, Fernando, Rodrigo Carlini, Zanatta, Daniela B., Strauss, Bryan Eric, Silva, Maria Regina Regis, Porcionatto, Marimélia Aparecida, Colleoni, Gisele Wally Braga
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2017
Soggetti:
Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5777725/
https://ncbi.nlm.nih.gov/pubmed/29383113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.22815
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