Transcriptome Analysis of Mesenchymal Stem Cells from Multiple Myeloma Patients Reveals Downregulation of Genes Involved in Cell Cycle Progression, Immune Response, and Bone Metabolism

A growing body of evidence suggests a key role of tumor microenvironment, especially for bone marrow mesenchymal stem cells (MSC), in the maintenance and progression of multiple myeloma (MM), through direct and indirect interactions with tumor plasma cells. Thus, this study aimed to investigate the...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Fernando, Rodrigo Carlini, Mazzotti, Diego Robles, Azevedo, Hatylas, Sandes, Alex Freire, Rizzatti, Edgar Gil, de Oliveira, Mariana Bleker, Alves, Veruska Lia Fook, Eugênio, Angela Isabel Pereira, de Carvalho, Fabrício, Dalboni, Maria Aparecida, Martins, David Correa, Colleoni, Gisele Wally Braga
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6355867/
https://ncbi.nlm.nih.gov/pubmed/30705326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-38314-8
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