Transcriptome Analysis of Mesenchymal Stem Cells from Multiple Myeloma Patients Reveals Downregulation of Genes Involved in Cell Cycle Progression, Immune Response, and Bone Metabolism

A growing body of evidence suggests a key role of tumor microenvironment, especially for bone marrow mesenchymal stem cells (MSC), in the maintenance and progression of multiple myeloma (MM), through direct and indirect interactions with tumor plasma cells. Thus, this study aimed to investigate the...

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Vydáno v:Sci Rep
Hlavní autoři: Fernando, Rodrigo Carlini, Mazzotti, Diego Robles, Azevedo, Hatylas, Sandes, Alex Freire, Rizzatti, Edgar Gil, de Oliveira, Mariana Bleker, Alves, Veruska Lia Fook, Eugênio, Angela Isabel Pereira, de Carvalho, Fabrício, Dalboni, Maria Aparecida, Martins, David Correa, Colleoni, Gisele Wally Braga
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6355867/
https://ncbi.nlm.nih.gov/pubmed/30705326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-38314-8
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