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1α,25-Dihydroxyvitamin D Inhibits de novo Fatty Acid Synthesis and Lipid Accumulation in Metastatic Breast Cancer Cells through Downregulation of Pyruvate Carboxylase
Both increased de novo fatty acid synthesis and higher neutral lipid accumulation are a common phenotype observed in aggressive breast cancer cells, making lipid metabolism a promising target for breast cancer prevention. In the present studies we demonstrate a novel effect of the active metabolite...
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| Yayımlandı: | J Nutr Biochem |
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| Asıl Yazarlar: | , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2016
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5777513/ https://ncbi.nlm.nih.gov/pubmed/27936456 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jnutbio.2016.11.006 |
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